A Daisy Can Kills Cancer Cells

Chamomile is a medicinal plant that we all know that has been used for centuries. Although it is said that it is good for migraine and other pains, it is debated whether or not it really helps. However, a study by researchers from the University of Birmingham found that a compound found in the leaves of this plant could have a lethal effect on cancer cells.

The name of this compound that has been investigated for years is parthenolide. While scientists suspect that this compound is an anti-cancer agent, it is both difficult and expensive to produce in consistent amounts.

Since chamomile and related plants have a high amount of parthenolide, the researchers have searched which one would be the best candidate to obtain the compound. After a few tests, they found that the highest amount of daisy again occurred in the late part of the flowering cycle.

The researchers searched for new derivatives that could be the best candidates to obtain the substance from plants. After examining the 76 derivatives listed, it distinguished the species with the best bioavailability, that is, the one that would react best with living cells and had the best pharmacological properties.

The compound was found to be effective when tested in cultured cells against chronic lymphocytic leukemia type cancer. Parthenolide increases the amount of reactive oxygen species (ROS), causing the death of cells. ROS is known to be higher in cancer cells. It is also being investigated that these reactive oxygen species may be potential bacterial agents. Therefore, the compound causes their destruction.
Lee Hale of Winterbourne Botanic Garden: After experimenting with similar plant species from the Asteraceae family, Tanacetum parthenium seems to contain the optimum parthenolide of white-leaf daisies. Perhaps this may produce a drug that kills cancer cells using parthenolide. In the next stage, you will try this compound in animals and most recently in humans.

The research was published in the journal MedChemComm. Below is a video of the study.

Source: University of Birmingham